I'm curious what the community thinking is on this point. While infinite scrolling may present a user-friendly tool for listing a large number of entries, isn't there potentially a downside from an SEO perspective IF the content in question doesn't have its own single entry screen which would expose an SEO-friendly semantic URL?
For blogs posts, for example, a common URL structure might be domain.com/blog to list most recent entries and a single blog post might be domain.com/blog/comments/entry-utl-title. EE then gives you a simple way to generate category-sorted lists using the category segment with something like domain.com/blog/category/category-url-title (and if you use addons you can also potentially achieve parenting segments, but not natively). I have to assume that the category url titles themselves are good for SEO as well, all things being equal.